Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 18/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 15/20 | 0.47 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22898779 | 1.00 | TLR7 (0.47) | TLR7TLR8NUDT1 | |
| SCHEMBL22898723 | 0.99 | TLR7 (0.48) | TLR7TLR8NUDT1 | |
| Formic Acid SCHEMBL27211547 | 0.95 | TLR7 (0.43) | TLR7TLR8NUDT1 | |
| SCHEMBL29606013 | 0.90 | TLR7 (0.41) | TLR7TLR8NUDT1 | |
| SCHEMBL27211546 | 0.90 | TLR7 (0.41) | TLR7TLR8NUDT1 | |
| SCHEMBL1538304 | 0.89 | TLR7 (0.59) | TLR7TLR8NUDT1 | |
| Water SCHEMBL29421423 | 0.88 | TLR7 (0.58) | TLR7TLR8NUDT1 | |
| Water SCHEMBL622142 | 0.88 | TLR7 (0.58) | TLR7TLR8NUDT1 | |
| SCHEMBL22898710 | 0.84 | TLR7 (0.46) | TLR7TLR8 | |
| SCHEMBL29605457 | 0.84 | TLR7 (0.46) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114364677-B | Imidazo [4,5-C ] pyridine derivatives as TOLL-like receptor agonists | 辉瑞公司 | 2024-07-09 | — | — | CN | claimed |
| EP-3999507-A1 | IMIDAZO[4,5-C]PYRIDINE DERIVATIVES AS TOLL-LIKE RECEPTOR AGONISTS | Pfizer Inc. (US) | 2022-05-25 | — | — | EP | claimed |
| CN-114364677-A | Imidazo [4,5-C ] pyridine derivatives as TOLL-like receptor agonists | 辉瑞公司 | 2022-04-15 | — | — | CN | claimed |
| CN-114364677-B | Imidazo [4,5-C ] pyridine derivatives as TOLL-like receptor agonists | 辉瑞公司 | 2024-07-09 | — | — | CN | disclosed |
| EP-3999507-A1 | IMIDAZO[4,5-C]PYRIDINE DERIVATIVES AS TOLL-LIKE RECEPTOR AGONISTS | Pfizer Inc. (US) | 2022-05-25 | — | — | EP | disclosed |
| CN-114364677-A | Imidazo [4,5-C ] pyridine derivatives as TOLL-like receptor agonists | 辉瑞公司 | 2022-04-15 | — | — | CN | disclosed |