Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 10/20 | 0.61 |
| ▸ | HDAC4 | P56524 | 10/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.61 |
| ▸ | HDAC7 | Q8WUI4 | 10/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.61 |
| ▸ | HDAC10 | Q969S8 | 10/20 | 0.61 |
| ▸ | HDAC11 | Q96DB2 | 10/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 10/20 | 0.61 |
| ▸ | HDAC9 | Q9UKV0 | 10/20 | 0.61 |
| ▸ | HDAC5 | Q9UQL6 | 10/20 | 0.61 |
| ▸ | NCOR2 | Q9Y618 | 10/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29110785 | 1.00 | HDAC6 (0.61) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29110756 | 0.90 | HDAC6 (0.50) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29606594 | 0.90 | HDAC6 (0.50) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29110750 | 0.88 | HDAC6 (0.51) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29605171 | 0.88 | HDAC6 (0.51) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29110779 | 0.86 | HDAC6 (0.55) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29606064 | 0.86 | HDAC6 (0.55) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29606043 | 0.86 | HDAC6 (0.68) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29110784 | 0.86 | HDAC6 (0.68) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29606031 | 0.85 | HDAC6 (0.67) | HDAC6HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621194-B | 4-methylene-N-hydroxybenzoamide compound and application thereof | 沈阳药科大学 | 2023-08-29 | — | — | CN | disclosed |
| CN-114621194-A | 4-methylene-N-hydroxybenzamide compound and application thereof | 沈阳药科大学 | 2022-06-14 | — | — | CN | disclosed |