Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 15/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 16/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 12/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 12/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 12/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 12/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 12/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 12/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 12/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 12/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 12/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 12/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | SCN4A | P35499 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29110742 | 1.00 | HDAC1 (0.53) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL29110798 | 0.93 | HDAC6 (0.52) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL29605581 | 0.93 | HDAC6 (0.52) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL29606484 | 0.89 | HDAC1 (0.51) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL29110735 | 0.89 | HDAC1 (0.51) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL29606259 | 0.88 | HDAC6 (0.46) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL29110787 | 0.88 | HDAC6 (0.46) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL29606339 | 0.88 | CYP2C9 (0.52) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL29110790 | 0.88 | CYP2C9 (0.52) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL29110801 | 0.88 | HDAC6 (0.52) | HDAC1HDAC6HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621194-B | 4-methylene-N-hydroxybenzoamide compound and application thereof | 沈阳药科大学 | 2023-08-29 | — | — | CN | disclosed |
| CN-114621194-A | 4-methylene-N-hydroxybenzamide compound and application thereof | 沈阳药科大学 | 2022-06-14 | — | — | CN | disclosed |