SCHEMBL29607288

SCHEMBL29607288

CCCCc1nc2c(N)nc(C)c(C)c2n1CC(C)(CO)CO

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.50
TLR8 Q9NR97 9/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22898735 1.00 TLR7 (0.50) TLR7TLR8
SCHEMBL5056931 0.88 TLR7 (0.64) TLR7TLR8
SCHEMBL29605589 0.82 TLR7 (0.51) TLR7TLR8
SCHEMBL22898778 0.82 TLR7 (0.51) TLR7TLR8
SCHEMBL22898789 0.82 TLR7 (0.32) TLR7TLR8
SCHEMBL29606601 0.82 TLR7 (0.32) TLR7TLR8
SCHEMBL22898872 0.79 TLR7 (0.80) TLR7TLR8
SCHEMBL22898754 0.79 TLR7 (0.46) TLR7TLR8
SCHEMBL22898710 0.79 TLR7 (0.46) TLR7TLR8
SCHEMBL5031335 0.79 TLR7 (0.44) TLR7TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114364677-B Imidazo [4,5-C ] pyridine derivatives as TOLL-like receptor agonists 辉瑞公司 2024-07-09 CN claimed
EP-3999507-A1 IMIDAZO[4,5-C]PYRIDINE DERIVATIVES AS TOLL-LIKE RECEPTOR AGONISTS Pfizer Inc. (US) 2022-05-25 EP claimed
CN-114364677-A Imidazo [4,5-C ] pyridine derivatives as TOLL-like receptor agonists 辉瑞公司 2022-04-15 CN claimed
CN-114364677-B Imidazo [4,5-C ] pyridine derivatives as TOLL-like receptor agonists 辉瑞公司 2024-07-09 CN disclosed
EP-3999507-A1 IMIDAZO[4,5-C]PYRIDINE DERIVATIVES AS TOLL-LIKE RECEPTOR AGONISTS Pfizer Inc. (US) 2022-05-25 EP disclosed
CN-114364677-A Imidazo [4,5-C ] pyridine derivatives as TOLL-like receptor agonists 辉瑞公司 2022-04-15 CN disclosed