SCHEMBL29610801

SCHEMBL29610801

Clc1ccc(-c2ccc(N(c3ccc(-c4ccc5ccccc5c4)cc3)c3ccc(-c4ccc5ccccc5c4)cc3)cc2)cc1Cl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 3/20 0.48
ESR2 Q92731 4/20 0.47
ESR1 P03372 3/20 0.47
CYP1B1 Q16678 1/20 0.42
ALOX5 P09917 1/20 0.42
BCL2L1 Q07817 1/20 0.41
MCL1 Q07820 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
HSD17B1 P14061 1/20 0.41
HSD17B2 P37059 1/20 0.41
FTO Q9C0B1 1/20 0.40
CYP2A6 P11509 1/20 0.39
EGFR P00533 1/20 0.39
ERBB2 P04626 1/20 0.39
ERBB3 P21860 1/20 0.39
KDR P35968 1/20 0.39
PTK2 Q05397 1/20 0.39
GSTP1 P09211 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24307501 1.00 AHR (0.48) AHRESR2ESR1CYP1B1ALOX5
SCHEMBL25736310 0.87 ESR1 (0.59) ESR2ESR1ALOX5CA1CA2
SCHEMBL21076148 0.87 AHR (0.64) AHRESR2ESR1CYP1B1ALOX5
SCHEMBL19269566 0.87 ESR1 (0.59) ESR2ESR1ALOX5CA1CA2
SCHEMBL12885982 0.85 ESR1 (0.57) ESR2ESR1ALOX5CA1CA2
SCHEMBL14490069 0.83 ESR1 (0.55) ESR2ESR1CYP1B1ALOX5CA1
SCHEMBL20313369 0.83 ESR1 (0.55) ESR2ESR1CYP1B1ALOX5CA1
SCHEMBL14490061 0.83 ESR1 (0.55) ESR2ESR1CYP1B1ALOX5CA1
SCHEMBL21834815 0.83 ESR1 (0.55) ESR2ESR1CYP1B1ALOX5CA1
SCHEMBL6372569 0.83 ESR1 (0.55) ESR2ESR1CYP1B1ALOX5CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116349429-A Arylamine compound, organic electroluminescent element, and electronic device 保土谷化学工业株式会社 2023-06-27 CN disclosed
WO-2022080490-A1 ARYLAMINE COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE 保土谷化学工業株式会社 2022-04-21 WO disclosed