Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAK4 | O96013 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.33 |
| ▸ | MAP3K12 | Q12852 | 3/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16345166 | 1.00 | PAK4 (0.43) | PAK4NAMPTPAK1HRH3MAP3K12 | |
| SCHEMBL16379559 | 0.90 | PAK4 (0.52) | PAK4NAMPTPAK1HRH3GABRA5 | |
| SCHEMBL29611290 | 0.90 | PAK4 (0.52) | PAK4NAMPTPAK1HRH3GABRA5 | |
| SCHEMBL18325831 | 0.88 | PAK4 (0.44) | PAK4NAMPTPAK1HRH3GABRA5 | |
| SCHEMBL16345033 | 0.87 | PAK4 (0.49) | PAK4NAMPTPAK1HRH3GABRA5 | |
| SCHEMBL16379641 | 0.84 | PAK4 (0.49) | PAK4NAMPTPAK1HRH3GABRA5 | |
| SCHEMBL29611088 | 0.84 | PAK4 (0.51) | PAK4NAMPTPAK1HRH3GABRA5 | |
| SCHEMBL16345462 | 0.84 | PAK4 (0.51) | PAK4NAMPTPAK1HRH3GABRA5 | |
| SCHEMBL16379753 | 0.83 | PAK4 (0.47) | PAK4NAMPTPAK1GABRA5SCN9A | |
| SCHEMBL31622635 | 0.83 | PAK4 (0.34) | PAK4MAP3K12GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440515-B | Substituted benzofuranyl and benzoxazolyl compounds and uses thereof | 卡尔约药物治疗公司 | 2022-05-03 | — | — | CN | disclosed |