Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 1.00 |
| ▸ | HTR2C | P28335 | 4/20 | 1.00 |
| ▸ | HTR2B | P41595 | 3/20 | 1.00 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.51 |
| ▸ | HTR1D | P28221 | 2/20 | 0.51 |
| ▸ | HTR1B | P28222 | 2/20 | 0.51 |
| ▸ | HTR7 | P34969 | 2/20 | 0.51 |
| ▸ | HTR6 | P50406 | 2/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL274662 | 1.00 | HTR2A (1.00) | HTR2AHTR2CHTR2BGPR84FFAR1 | |
| Hydrochloric Acid SCHEMBL273182 | 0.98 | HTR2A (0.97) | HTR2AHTR2CHTR2BGPR84FFAR1 | |
| SCHEMBL1248753 | 0.86 | HTR2A (0.76) | HTR2AHTR2CHTR2BGPR84FFAR1 | |
| SCHEMBL10070049 | 0.84 | HTR2A (0.72) | HTR2AHTR2CHTR2BGPR84FFAR1 | |
| SCHEMBL12671597 | 0.84 | HTR2A (0.72) | HTR2AHTR2CHTR2BGPR84FFAR1 | |
| SCHEMBL12671700 | 0.84 | HTR2A (0.72) | HTR2AHTR2CHTR2BGPR84FFAR1 | |
| SCHEMBL6977846 | 0.82 | HTR2A (0.70) | HTR2AHTR2CHTR2BGPR84FFAR1 | |
| SCHEMBL18856896 | 0.82 | HTR2A (0.70) | HTR2AHTR2CHTR2BGPR84FFAR1 | |
| SCHEMBL6823826 | 0.81 | MEN1 (0.70) | HTR2AHTR2CHTR2BGPR84FFAR1 | |
| SCHEMBL29287871 | 0.81 | HTR2A (0.68) | HTR2AHTR2CHTR2BGPR84FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116535403-B | Beta-carbopol derivative and preparation method, pharmaceutical composition and application thereof | 沈阳药科大学 | 2024-12-03 | — | — | CN | disclosed |
| CN-110831600-B | Indole AHR inhibitors and uses thereof | 医肯纳肿瘤学公司 | 2023-10-17 | — | — | CN | disclosed |
| CN-116535403-A | Beta-carbopol derivative and preparation method, pharmaceutical composition and application thereof | 沈阳药科大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-109311876-B | Heteroaryl estrogen receptor modulators and uses thereof | 豪夫迈·罗氏有限公司 | 2022-05-03 | — | — | CN | disclosed |