SCHEMBL29611539

SCHEMBL29611539

CCCCCS(=O)(=O)NC(=O)c1ccc2nc(C)n(Cc3ccc(Cl)c(Cl)c3)c2c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 10/20 0.74
HDAC1 Q13547 3/20 0.46
HDAC6 Q9UBN7 3/20 0.46
RORC P51449 1/20 0.43
IRAK4 Q9NWZ3 1/20 0.43
AGTR1 P30556 1/20 0.43
AGTR2 P50052 1/20 0.43
HDAC3 O15379 2/20 0.43
HDAC4 P56524 2/20 0.43
HDAC7 Q8WUI4 2/20 0.43
HDAC2 Q92769 2/20 0.43
HDAC10 Q969S8 2/20 0.43
HDAC11 Q96DB2 2/20 0.43
HDAC8 Q9BY41 2/20 0.43
HDAC9 Q9UKV0 2/20 0.43
HDAC5 Q9UQL6 2/20 0.43
CCR2 P41597 1/20 0.42
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.41
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6301169 0.89 PPARG (0.84) PPARGHDAC1HDAC6RORCHDAC3
SCHEMBL6301327 0.88 PPARG (0.83) PPARGHDAC1HDAC6RORCAGTR1
SCHEMBL6308137 0.88 PPARG (0.83) PPARGHDAC1HDAC6RORCAGTR1
SCHEMBL7650777 0.87 PPARG (0.91) PPARGHDAC1HDAC6RORCIRAK4
SCHEMBL6301610 0.87 PPARG (0.81) PPARGHDAC1HDAC6RORCAGTR1
SCHEMBL6134679 0.87 PPARG (0.81) PPARGHDAC1HDAC6RORCAGTR1
SCHEMBL6472946 0.86 PPARG (0.79) PPARGHDAC1HDAC6RORCHDAC3
SCHEMBL1160303 0.86 PPARG (0.82) PPARGHDAC1HDAC6RORCIRAK4
SCHEMBL6303482 0.85 PPARG (0.79) PPARGHDAC1HDAC6RORCAGTR1
SCHEMBL7650594 0.85 PPARG (0.78) PPARGHDAC1HDAC6RORCAGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250073171-A1 DRUG DELIVERY SYSTEM FOR THE TREATMENT OF FEMALE SEXUAL INTEREST AND AROUSAL DISORDER Freya Pharma Solutions Holding B.V. (NL) 2025-03-06 US disclosed
US-12186322-B2 Liquid oral formulations for tadalafil LIQMEDS WORLDWIDE LIMITED (GB) 2025-01-07 US disclosed
US-12186321-B2 Liquid oral formulations for sildenafil LIQMEDS WORLDWIDE LIMITED (GB) 2025-01-07 US disclosed
US-20240299396-A1 LIQUID ORAL FORMULATIONS FOR PDE V INHIBITORS LIQMEDS WORLDWIDE LIMITED (GB) 2024-09-12 US disclosed
US-20240245688-A1 LIQUID ORAL FORMULATIONS FOR TADALAFIL LIQMEDS WORLDWIDE LIMITED (GB) 2024-07-25 US disclosed
US-20240245689-A1 LIQUID ORAL FORMULATIONS FOR SILDENAFIL LIQMEDS WORLDWIDE LIMITED (GB) 2024-07-25 US disclosed
US-12005062-B2 Liquid oral formulations for sildenafil LIQMEDS WORLDWIDE LIMITED (GB) 2024-06-11 US disclosed
US-20240165032-A1 DRUG DELIVERY SYSTEM EB IP HYBRITABS B V (NL) 2024-05-23 US disclosed
US-11975006-B2 Liquid oral formulations for tadalafil LIQMEDS WORLDWIDE LIMITED (GB) 2024-05-07 US disclosed
US-20230381187-A1 LIQUID ORAL FORMULATIONS FOR SILDENAFIL LIQMEDS WORLDWIDE LIMITED (GB) 2023-11-30 US disclosed
US-20230330028-A1 PROCESS FOR THE PREPARATION OF DRUG DELIVERY SYSTEMS HAVING A TESTOSTERONE COMPOUND PRESENT IN AN OUTER LAYER OR PART, AS WELL AS SUCH DRUG DELIVERY SYSTEMS EB IP HYBRITABS B.V. (NL) 2023-10-19 US disclosed
US-11759468-B2 Liquid oral formulations for sildenafil LIQMEDS WORLDWIDE LIMITED (GB) 2023-09-19 US disclosed
US-20230285398-A1 LIQUID ORAL FORMULATIONS FOR TADALAFIL LIQMEDS WORLDWIDE LIMITED (GB) 2023-09-14 US disclosed
US-11666576-B2 Liquid oral formulations for tadalafil LIQMEDS WORLDWIDE LIMITED (GB) 2023-06-06 US disclosed
US-20220409621-A1 LIQUID ORAL FORMULATIONS FOR SILDENAFIL LIQMEDS WORLDWIDE LIMITED (GB) 2022-12-29 US disclosed
CN-109414402-B Method for preparing a drug delivery system with a testosterone compound present externally or topically and such a drug delivery system EB IP希博里塔布斯有限责任公司 2022-11-04 CN disclosed
US-11464778-B2 Liquid oral formulations for sildenafil LIQMEDS WORLDWIDE LIMITED (GB) 2022-10-11 US disclosed
US-20220296602-A1 LIQUID ORAL FORMULATIONS FOR TADALAFIL LIQMEDS WORLDWIDE LIMITED (GB) 2022-09-22 US disclosed
US-11382917-B2 Liquid oral formulations for tadalafil LIQMEDS WORLDWIDE LIMITED (GB) 2022-07-12 US disclosed
US-11337979-B2 Liquid oral formulations for sildenafil LIQMEDS WORLDWIDE LIMITED (GB) 2022-05-24 US disclosed