SCHEMBL29611957

SCHEMBL29611957

CCCOc1ccc(C(=O)CN2CCOCC2)cc1-c1nc2c(CCC)nn(C)c2c(=O)[nH]1

nearest known ligand 0.90

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PDE5A O76074 20/20 0.90
PDE6C P51160 2/20 0.90
HDAC1 Q13547 4/20 0.57
HDAC6 Q9UBN7 4/20 0.57
HDAC2 Q92769 3/20 0.57
HDAC3 O15379 1/20 0.55
NCOR2 Q9Y618 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL146830 1.00 PDE5A (0.90) PDE5APDE6CHDAC1HDAC6HDAC2
SCHEMBL147337 0.95 PDE5A (1.00) PDE5APDE6CHDAC1HDAC6HDAC2
SCHEMBL18069561 0.92 PDE5A (0.77) PDE5APDE6CHDAC1HDAC6HDAC2
SCHEMBL7959160 0.92 PDE5A (0.77) PDE5APDE6CHDAC1HDAC6HDAC2
SCHEMBL5964550 0.88 PDE5A (0.70) PDE5APDE6CHDAC1HDAC6HDAC2
SCHEMBL7965731 0.88 PDE5A (0.84) PDE5APDE6CHDAC1HDAC6HDAC2
SCHEMBL25013469 0.87 PDE5A (0.85) PDE5APDE6CHDAC1HDAC6HDAC2
SCHEMBL29357402 0.87 PDE5A (0.85) PDE5APDE6CHDAC1HDAC6HDAC2
SCHEMBL7964961 0.87 PDE5A (0.85) PDE5APDE6CHDAC1HDAC6HDAC2
SCHEMBL30199753 0.87 PDE5A (0.85) PDE5APDE6CHDAC1HDAC6HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12186322-B2 Liquid oral formulations for tadalafil LIQMEDS WORLDWIDE LIMITED (GB) 2025-01-07 US disclosed
US-12186321-B2 Liquid oral formulations for sildenafil LIQMEDS WORLDWIDE LIMITED (GB) 2025-01-07 US disclosed
US-20240299396-A1 LIQUID ORAL FORMULATIONS FOR PDE V INHIBITORS LIQMEDS WORLDWIDE LIMITED (GB) 2024-09-12 US disclosed
US-20240245688-A1 LIQUID ORAL FORMULATIONS FOR TADALAFIL LIQMEDS WORLDWIDE LIMITED (GB) 2024-07-25 US disclosed
US-20240245689-A1 LIQUID ORAL FORMULATIONS FOR SILDENAFIL LIQMEDS WORLDWIDE LIMITED (GB) 2024-07-25 US disclosed
US-12005062-B2 Liquid oral formulations for sildenafil LIQMEDS WORLDWIDE LIMITED (GB) 2024-06-11 US disclosed
US-11975006-B2 Liquid oral formulations for tadalafil LIQMEDS WORLDWIDE LIMITED (GB) 2024-05-07 US disclosed
US-20230381187-A1 LIQUID ORAL FORMULATIONS FOR SILDENAFIL LIQMEDS WORLDWIDE LIMITED (GB) 2023-11-30 US disclosed
US-11759468-B2 Liquid oral formulations for sildenafil LIQMEDS WORLDWIDE LIMITED (GB) 2023-09-19 US disclosed
US-20230285398-A1 LIQUID ORAL FORMULATIONS FOR TADALAFIL LIQMEDS WORLDWIDE LIMITED (GB) 2023-09-14 US disclosed
US-11666576-B2 Liquid oral formulations for tadalafil LIQMEDS WORLDWIDE LIMITED (GB) 2023-06-06 US disclosed
US-20220409621-A1 LIQUID ORAL FORMULATIONS FOR SILDENAFIL LIQMEDS WORLDWIDE LIMITED (GB) 2022-12-29 US disclosed
US-11464778-B2 Liquid oral formulations for sildenafil LIQMEDS WORLDWIDE LIMITED (GB) 2022-10-11 US disclosed
US-20220296602-A1 LIQUID ORAL FORMULATIONS FOR TADALAFIL LIQMEDS WORLDWIDE LIMITED (GB) 2022-09-22 US disclosed
US-11382917-B2 Liquid oral formulations for tadalafil LIQMEDS WORLDWIDE LIMITED (GB) 2022-07-12 US disclosed
US-11337979-B2 Liquid oral formulations for sildenafil LIQMEDS WORLDWIDE LIMITED (GB) 2022-05-24 US disclosed