Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI4 | Q9UM07 | 16/20 | 0.64 |
| ▸ | MAP2 | P11137 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CSF1R | P07333 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19952854 | 1.00 | PADI4 (0.64) | PADI4MAP2MEN1KMT2ACSF1R | |
| SCHEMBL19952864 | 0.89 | PADI4 (0.66) | PADI4MAP2 | |
| Lithium Ion SCHEMBL28759891 | 0.86 | PADI4 (0.62) | PADI4MAP2 | |
| SCHEMBL29612310 | 0.85 | PADI4 (0.73) | PADI4MAP2MEN1KMT2ACSF1R | |
| SCHEMBL19952906 | 0.85 | PADI4 (0.73) | PADI4MAP2MEN1KMT2ACSF1R | |
| SCHEMBL14304852 | 0.85 | MAP2 (0.75) | PADI4MAP2MEN1KMT2ACSF1R | |
| SCHEMBL16112039 | 0.84 | MEN1 (0.76) | PADI4MAP2MEN1KMT2ACSF1R | |
| SCHEMBL30043560 | 0.84 | MAP2 (0.74) | PADI4MAP2CSF1R | |
| SCHEMBL6059495 | 0.84 | MAP2 (0.74) | PADI4MAP2CSF1R | |
| SCHEMBL29612100 | 0.83 | KDM4E (0.68) | PADI4MAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110248934-B | Heteroaryl PAD4 inhibitors | 帕德罗科治疗公司 | 2022-05-24 | — | — | CN | disclosed |