Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 8/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 6/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | REN | P00797 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19252770 | 1.00 | PDE4A (0.42) | PDE4APDE4BPDE4DPDE4CTP53 | |
| SCHEMBL21175971 | 0.87 | SLC6A4 (0.36) | PDE4APDE4BPDE4DPDE4CTP53 | |
| SCHEMBL29613172 | 0.80 | PDE4A (0.43) | PDE4APDE4BPDE4DPDE4CTP53 | |
| SCHEMBL18425422 | 0.80 | PDE4A (0.43) | PDE4APDE4BPDE4DPDE4CTP53 | |
| SCHEMBL19252806 | 0.78 | HTR2C (0.42) | PDE4APDE4BPDE4DPDE4CTP53 | |
| SCHEMBL19270708 | 0.78 | NPC1 (0.39) | PDE4APDE4BPDE4DPDE4CTP53 | |
| SCHEMBL18424220 | 0.77 | PDE4A (0.42) | PDE4APDE4BPDE4DPDE4CTP53 | |
| SCHEMBL19252773 | 0.77 | PDE4A (0.42) | PDE4APDE4BPDE4DPDE4CREN | |
| SCHEMBL29613142 | 0.77 | PDE4A (0.42) | PDE4APDE4BPDE4DPDE4CREN | |
| SCHEMBL19259465 | 0.76 | PDE4A (0.44) | PDE4APDE4BPDE4DPDE4CREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071447-B | Tetracyclic pyridinone compounds as antiviral agents | 诺华股份有限公司 | 2022-04-22 | — | — | CN | disclosed |