Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.49 |
| ▸ | RORC | P51449 | 9/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 2/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | SMO | Q99835 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.36 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19786009 | 1.00 | PTGDR2 (0.49) | PTGDR2RORCKCNH2CCR1DHODH | |
| SCHEMBL21368756 | 0.92 | PTGDR2 (0.49) | PTGDR2RORCKCNH2CCR1DHODH | |
| SCHEMBL19786001 | 0.89 | PTGDR2 (0.48) | PTGDR2RORCKCNH2CCR1DHODH | |
| SCHEMBL29613279 | 0.89 | PTGDR2 (0.48) | PTGDR2RORCKCNH2CCR1DHODH | |
| SCHEMBL19785909 | 0.87 | PTGDR2 (0.50) | PTGDR2RORCKCNH2CCR1DHODH | |
| SCHEMBL21354245 | 0.87 | PTGDR2 (0.50) | PTGDR2RORCKCNH2CCR1DHODH | |
| SCHEMBL29613549 | 0.87 | PTGDR2 (0.50) | PTGDR2RORCKCNH2CCR1DHODH | |
| SCHEMBL21354355 | 0.86 | PTGDR2 (0.49) | PTGDR2RORCKCNH2CCR1DHODH | |
| SCHEMBL19786057 | 0.86 | PTGDR2 (0.51) | PTGDR2RORCKCNH2CCR1DHODH | |
| SCHEMBL21354360 | 0.83 | PTGDR2 (0.46) | PTGDR2RORCKCNH2CCR1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476653-B | Heteroaromatic modulators of retinoid-related orphan receptor gamma | 利奥制药有限公司 | 2022-04-22 | — | — | CN | claimed |
| CN-109476653-B | Heteroaromatic modulators of retinoid-related orphan receptor gamma | 利奥制药有限公司 | 2022-04-22 | — | — | CN | disclosed |