Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 3/20 | 0.47 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.43 |
| ▸ | GRB2 | P62993 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.42 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.41 |
| ▸ | CBX4 | O00257 | 1/20 | 0.41 |
| ▸ | CBX7 | O95931 | 1/20 | 0.41 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.41 |
| ▸ | CBX8 | Q9HC52 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29613492 | 1.00 | TLR2 (0.47) | TLR2TLR1KMT2APTPN1GRB2 | |
| SCHEMBL29613476 | 0.95 | KMT2A (0.52) | TLR2TLR1KMT2AMDM2KLK7 | |
| SCHEMBL29129048 | 0.94 | KMT2A (0.49) | TLR2TLR1KMT2APTPN1GRB2 | |
| SCHEMBL29129044 | 0.94 | KMT2A (0.49) | TLR2TLR1KMT2APTPN1GRB2 | |
| SCHEMBL13289729 | 0.92 | TLR2 (0.48) | TLR2TLR1KMT2APTPN1GRB2 | |
| SCHEMBL29613412 | 0.92 | KLK7 (0.49) | TLR2TLR1KMT2APTPN1KLK7 | |
| SCHEMBL29613446 | 0.90 | PTPN1 (0.50) | TLR2TLR1KMT2APTPN1GRB2 | |
| SCHEMBL16790462 | 0.89 | KMT2A (0.50) | TLR2TLR1KMT2AMDM2KLK7 | |
| SCHEMBL27223065 | 0.89 | KMT2A (0.54) | TLR2TLR1KMT2AMDM2KLK7 | |
| SCHEMBL27231537 | 0.89 | KMT2A (0.54) | TLR2TLR1KMT2AMDM2KLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4259133-A1 | METHODS AND COMPOUNDS FOR MODULATING MYOTONIC DYSTROPHY 1 | Design Therapeutics, Inc. (US) | 2023-10-18 | — | — | EP | disclosed |
| WO-2022126000-A1 | METHODS AND COMPOUNDS FOR MODULATING MYOTONIC DYSTROPHY 1 | Design Therapeutics, Inc. (US) | 2022-06-16 | — | — | WO | disclosed |