SCHEMBL29613621

SCHEMBL29613621

O=C(NN=Cc1ccc2c(ccn2Cc2ccc(Cl)s2)c1)c1ccc(O)c(Cl)c1

nearest known ligand 0.66

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GCGR P47871 15/20 0.66
ADCYAP1R1 P41586 5/20 0.47
DNM1 Q05193 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2662497 1.00 GCGR (0.66) GCGRADCYAP1R1DNM1
SCHEMBL9071578 0.91 GCGR (0.56) GCGRADCYAP1R1DNM1
SCHEMBL9071586 0.84 GCGR (0.76) GCGRADCYAP1R1
SCHEMBL9071584 0.82 GCGR (0.73) GCGRADCYAP1R1
SCHEMBL9071587 0.82 GCGR (0.72) GCGRADCYAP1R1
SCHEMBL2662794 0.82 GCGR (0.73) GCGRADCYAP1R1
SCHEMBL2662672 0.81 GCGR (0.69) GCGRADCYAP1R1
SCHEMBL9071579 0.80 GCGR (0.72) GCGRADCYAP1R1
SCHEMBL9071689 0.80 GCGR (1.00) GCGRADCYAP1R1
SCHEMBL2662809 0.79 ADCYAP1R1 (0.73) GCGRADCYAP1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3569248-B1 GIP INHIBITORS FOR IMPROVING COGNITIVE FUNCTION KAO CORP (JP) 2023-12-06 EP claimed
EP-3560515-B1 GIP INHIBITORS FOR USE IN IMPROVING MOTOR CONTROL FUNCTION KAO CORP (JP) 2023-11-15 EP claimed
EP-3569248-B1 GIP INHIBITORS FOR IMPROVING COGNITIVE FUNCTION KAO CORP (JP) 2023-12-06 EP disclosed
EP-3560515-B1 GIP INHIBITORS FOR USE IN IMPROVING MOTOR CONTROL FUNCTION KAO CORP (JP) 2023-11-15 EP disclosed
US-11555069-B2 Cognitive function improving agent KAO CORPORATION (JP) 2023-01-17 US disclosed
US-11319369-B2 Motor control function improving agent KAO CORPORATION (JP) 2022-05-03 US disclosed