Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.55 |
| ▸ | DPP3 | Q9NY33 | 5/20 | 0.48 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | KRAS | P01116 | 1/20 | 0.43 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 2/20 | 0.42 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.42 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16704179 | 1.00 | DPP4 (0.55) | DPP4DPP3SNCAKRASSOS1 | |
| SCHEMBL20853453 | 1.00 | DPP4 (0.55) | DPP4DPP3SNCAKRASSOS1 | |
| SCHEMBL16704181 | 1.00 | DPP4 (0.55) | DPP4DPP3SNCAKRASSOS1 | |
| Hydrochloric Acid SCHEMBL16704302 | 0.99 | DPP4 (0.54) | DPP4DPP3SNCAKRASSOS1 | |
| Hydrochloric Acid SCHEMBL18094977 | 0.99 | DPP4 (0.54) | DPP4DPP3SNCAKRASSOS1 | |
| Hydrochloric Acid SCHEMBL16704300 | 0.99 | DPP4 (0.54) | DPP4DPP3SNCAKRASSOS1 | |
| Hydrochloric Acid SCHEMBL28888416 | 0.99 | DPP4 (0.54) | DPP4DPP3SNCAKRASSOS1 | |
| SCHEMBL16703980 | 0.90 | DPP3 (0.49) | DPP4DPP3SNCABCHETACR1 | |
| SCHEMBL16703025 | 0.85 | DPP4 (0.54) | DPP4 | |
| SCHEMBL20853463 | 0.85 | DPP4 (0.54) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4001272-B1 | NMDA ANTAGONIST PRODRUGS | ASTRAZENECA AB (SE) | 2024-11-13 | — | — | EP | claimed |
| EP-4001272-A1 | NMDA ANTAGONIST PRODRUGS | Astrazeneca AB (SE) | 2022-05-25 | — | — | EP | claimed |
| EP-4580679-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND NMDA RECEPTOR ANTAGONISTS | Biohaven Therapeutics Ltd. (VG) | 2025-07-09 | — | — | EP | disclosed |
| WO-2024050389-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND NMDA RECEPTOR ANTAGONISTS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-07 | — | — | WO | disclosed |