Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22899659 | 1.00 | TOP2A (0.31) | TOP2ACYP3A4 | |
| SCHEMBL22899719 | 0.91 | — | — | |
| SCHEMBL22899590 | 0.91 | — | — | |
| SCHEMBL27195123 | 0.89 | CYP3A4 (0.30) | CYP3A4 | |
| SCHEMBL22899715 | 0.84 | NT5E (0.32) | — | |
| SCHEMBL29613885 | 0.84 | NT5E (0.32) | — | |
| SCHEMBL22899554 | 0.84 | — | — | |
| SCHEMBL22899656 | 0.83 | NT5E (0.33) | — | |
| SCHEMBL22899496 | 0.82 | NT5E (0.33) | — | |
| SCHEMBL29613863 | 0.82 | NT5E (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12544391-B2 | CD73 inhibitors | ORIC PHARMACEUTICALS, INC. (US) | 2026-02-10 | — | — | US | disclosed |
| US-20220331343-A1 | CD73 INHIBITORS | ORIC PHARMACEUTICALS, INC. | 2022-10-20 | — | — | US | disclosed |
| EP-3999517-A1 | CD73 INHIBITORS | Oric Pharmaceuticals, Inc. (US) | 2022-05-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12544391-B2 | CD73 inhibitors | NT5E, NTPCR, NT5C2 | TOP2A 1419/4885CYP3A4 2301/4885 |
| US-20220331343-A1 | CD73 INHIBITORS | ENTPD5, NT5E, ENTPD1 | TOP2A 1586/4885CYP3A4 2580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.