Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 19/20 | 0.53 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.50 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.49 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22776650 | 1.00 | PTGER4 (0.53) | PTGER4PTGER2PTGDRPTGER3RORC | |
| SCHEMBL22776648 | 1.00 | PTGER4 (0.53) | PTGER4PTGER2PTGDRPTGER3RORC | |
| SCHEMBL22776587 | 0.93 | PTGER4 (0.54) | PTGER4PTGER2PTGDRPTGER3 | |
| SCHEMBL22776588 | 0.93 | PTGER4 (0.54) | PTGER4PTGER2PTGDRPTGER3 | |
| SCHEMBL29614485 | 0.92 | PTGER4 (0.44) | PTGER4PTGER2PTGDRPTGER3RORC | |
| SCHEMBL22776442 | 0.92 | PTGER4 (0.44) | PTGER4PTGER2PTGDRPTGER3RORC | |
| SCHEMBL22776439 | 0.92 | PTGER4 (0.44) | PTGER4PTGER2PTGDRPTGER3RORC | |
| SCHEMBL22777144 | 0.88 | PTGER4 (0.53) | PTGER4PTGER2PTGDRPTGER3 | |
| SCHEMBL22777142 | 0.88 | PTGER4 (0.53) | PTGER4PTGER2PTGDRPTGER3 | |
| SCHEMBL29614449 | 0.88 | PTGER4 (0.53) | PTGER4PTGER2PTGDRPTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3983412-A1 | PROSTAGLANDIN E2 RECEPTOR 4 ANTAGONISTS AND USES THEREOF | Teon Therapeutics, Inc. (US) | 2022-04-20 | — | — | EP | disclosed |