Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24421152 | 1.00 | POLB (0.41) | POLBSMN1; SMN2 | |
| SCHEMBL2810511 | 0.73 | SMN1; SMN2 (0.56) | POLBSMN1; SMN2 | |
| SCHEMBL2806475 | 0.71 | POLB (0.57) | POLBSMN1; SMN2 | |
| SCHEMBL2807505 | 0.70 | POLB (0.56) | POLBSMN1; SMN2 | |
| SCHEMBL904189 | 0.69 | ACACB (0.41) | — | |
| SCHEMBL903973 | 0.68 | HDAC3 (0.36) | — | |
| SCHEMBL31597922 | 0.67 | POLB (0.49) | POLBSMN1; SMN2 | |
| SCHEMBL22720338 | 0.64 | SMN1; SMN2 (0.76) | POLBSMN1; SMN2 | |
| SCHEMBL12769043 | 0.62 | HTR2C (0.34) | — | |
| SCHEMBL8203125 | 0.61 | ACACB (0.50) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4240743-A1 | BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | Prelude Therapeutics, Incorporated (US) | 2023-09-13 | — | — | EP | disclosed |
| WO-2022099117-A1 | BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | PRELUDE THERAPEUTICS INCORPORATED (US) | 2022-05-12 | — | — | WO | disclosed |