Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 10/20 | 0.61 |
| ▸ | WIZ | O95785 | 5/20 | 0.56 |
| ▸ | IKZF2 | Q9UKS7 | 5/20 | 0.53 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20231317 | 1.00 | CRBN (0.61) | CRBNWIZIKZF2CSNK1A1 | |
| SCHEMBL20442557 | 1.00 | CRBN (0.61) | CRBNWIZIKZF2CSNK1A1 | |
| SCHEMBL20231099 | 0.91 | CRBN (0.62) | CRBNWIZIKZF2CSNK1A1 | |
| SCHEMBL20046456 | 0.91 | CRBN (0.62) | CRBNWIZIKZF2CSNK1A1 | |
| SCHEMBL26189743 | 0.87 | CRBN (0.46) | CRBNWIZIKZF2CSNK1A1 | |
| SCHEMBL22962697 | 0.87 | CRBN (0.66) | CRBNWIZIKZF2CSNK1A1 | |
| SCHEMBL34466761 | 0.86 | CRBN (0.65) | CRBNWIZIKZF2CSNK1A1 | |
| SCHEMBL34465960 | 0.86 | CRBN (0.65) | CRBNWIZIKZF2CSNK1A1 | |
| SCHEMBL22566723 | 0.86 | IKZF2 (0.65) | CRBNWIZIKZF2 | |
| SCHEMBL24291214 | 0.85 | CRBN (0.61) | CRBNWIZIKZF2CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4240743-A1 | BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | Prelude Therapeutics, Incorporated (US) | 2023-09-13 | — | — | EP | disclosed |
| WO-2022099117-A1 | BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | PRELUDE THERAPEUTICS INCORPORATED (US) | 2022-05-12 | — | — | WO | disclosed |