Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 19/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29614843 | 0.88 | KRAS (0.43) | KRAS | |
| SCHEMBL22848359 | 0.88 | KRAS (0.43) | KRAS | |
| SCHEMBL29614782 | 0.88 | KRAS (0.43) | KRAS | |
| SCHEMBL24436331 | 0.87 | KRAS (0.43) | KRAS | |
| SCHEMBL22848275 | 0.82 | KRAS (0.42) | KRAS | |
| SCHEMBL29614787 | 0.82 | KRAS (0.42) | KRAS | |
| SCHEMBL24436730 | 0.80 | KRAS (0.42) | KRAS | |
| SCHEMBL24436453 | 0.79 | KRAS (0.48) | KRAS | |
| SCHEMBL29614983 | 0.79 | KRAS (0.48) | KRAS | |
| SCHEMBL24436419 | 0.76 | KRAS (0.54) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3990448-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF KRAS G12C | Guangdong Newopp Biopharmaceuticals Co., Ltd. (CN) | 2022-05-04 | — | — | EP | disclosed |