Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK8 | O60259 | 20/20 | 0.84 |
| ▸ | F2 | P00734 | 20/20 | 0.84 |
| ▸ | KLKB1 | P03952 | 20/20 | 0.84 |
| ▸ | KLK14 | Q9P0G3 | 20/20 | 0.84 |
| ▸ | KLK5 | Q9Y337 | 20/20 | 0.84 |
| ▸ | ST14 | Q9Y5Y6 | 20/20 | 0.84 |
| ▸ | F10 | P00742 | 19/20 | 0.84 |
| ▸ | PLAU | P00749 | 13/20 | 0.84 |
| ▸ | KLK1 | P06870 | 10/20 | 0.84 |
| ▸ | KLK7 | P49862 | 6/20 | 0.84 |
| ▸ | ELANE | P08246 | 12/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23760832 | 1.00 | KLK8 (0.84) | KLK8F2KLKB1KLK14KLK5 | |
| SCHEMBL21590051 | 1.00 | KLK8 (0.84) | KLK8F2KLKB1KLK14KLK5 | |
| SCHEMBL21585884 | 0.92 | KLK8 (1.00) | KLK8F2KLKB1KLK14KLK5 | |
| SCHEMBL21585886 | 0.92 | KLK8 (1.00) | KLK8F2KLKB1KLK14KLK5 | |
| SCHEMBL21590048 | 0.92 | KLK8 (1.00) | KLK8F2KLKB1KLK14KLK5 | |
| SCHEMBL30712330 | 0.92 | KLK8 (1.00) | KLK8F2KLKB1KLK14KLK5 | |
| Hydrochloric Acid SCHEMBL23753668 | 0.91 | KLK8 (1.00) | KLK8F2KLKB1KLK14KLK5 | |
| Hydrochloric Acid SCHEMBL29615876 | 0.91 | KLK8 (1.00) | KLK8F2KLKB1KLK14KLK5 | |
| Hydrochloric Acid SCHEMBL23753671 | 0.91 | KLK8 (1.00) | KLK8F2KLKB1KLK14KLK5 | |
| Hydrochloric Acid SCHEMBL29615866 | 0.91 | KLK8 (1.00) | KLK8F2KLKB1KLK14KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3802550-B1 | NOVEL BENZIMIDAMIDES COMPOUNDS COMPRISING AN OXABORININ RING | INST NAT SANTE RECH MED (FR) | 2023-12-27 | — | — | EP | disclosed |
| US-11767333-B2 | Benzimidamides compounds comprising an oxaborinin ring | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2023-09-26 | — | — | US | disclosed |
| US-20220267357-A1 | Novel Benzimidamides Compounds Comprising an Oxaborinin Ring | INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (INSERM) (FR) | 2022-08-25 | — | — | US | disclosed |
| US-11352372-B2 | Benzimidamides compounds comprising an oxaborinin ring | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2022-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11352372-B2 | Benzimidamides compounds comprising an oxaborinin ring | KLKB1, KLK1, KLK5 | KLK8 6/4885F2 1430/4885KLKB1 1/4885 |
| US-20220267357-A1 | Novel Benzimidamides Compounds Comprising an Oxaborinin Ring | KLKB1, KLK1, KLK2 | KLK8 5/4885F2 1737/4885KLKB1 1/4885 |
| US-11767333-B2 | Benzimidamides compounds comprising an oxaborinin ring | KLKB1, KLK1, KLK2 | KLK8 6/4885F2 1549/4885KLKB1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.