Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 19/20 | 0.72 |
| ▸ | EZH1 | Q92800 | 8/20 | 0.69 |
| ▸ | EED | O75530 | 4/20 | 0.69 |
| ▸ | SUZ12 | Q15022 | 4/20 | 0.69 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.59 |
| ▸ | RBBP7 | Q16576 | 1/20 | 0.59 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12180174 | 1.00 | EZH2 (0.72) | EZH2EZH1EEDSUZ12RBBP4 | |
| SCHEMBL2594075 | 0.84 | EZH2 (1.00) | EZH2EZH1EEDSUZ12RBBP4 | |
| SCHEMBL15391128 | 0.83 | EZH2 (0.72) | EZH2EZH1EEDSUZ12RBBP4 | |
| SCHEMBL15390253 | 0.83 | EZH2 (0.72) | EZH2EZH1EEDSUZ12RBBP4 | |
| SCHEMBL19657082 | 0.83 | EZH2 (0.78) | EZH2EZH1EEDSUZ12RBBP4 | |
| SCHEMBL12180731 | 0.83 | EZH2 (0.88) | EZH2EZH1EEDSUZ12RBBP4 | |
| SCHEMBL2594100 | 0.83 | EZH2 (0.78) | EZH2EZH1EEDSUZ12RBBP4 | |
| SCHEMBL16360967 | 0.83 | EZH2 (0.80) | EZH2EZH1EEDSUZ12RBBP4 | |
| SCHEMBL16115907 | 0.82 | EZH2 (0.69) | EZH2EZH1EEDSUZ12RBBP4 | |
| SCHEMBL18768926 | 0.82 | EZH2 (0.88) | EZH2EZH1EEDSUZ12RBBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3990444-A1 | USE OF INHIBITORS OF ENHANCER OF ZESTE HOMOLOG 2 | The Board of Regents of The University of Texas System (US) | 2022-05-04 | — | — | EP | claimed |