Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 16/20 | 0.51 |
| ▸ | KIT | P10721 | 15/20 | 0.51 |
| ▸ | SRC | P12931 | 3/20 | 0.50 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.50 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29616334 | 0.91 | FLT3 (0.46) | FLT3KITSRCNTRK1KDR | |
| SCHEMBL28912502 | 0.90 | FLT3 (0.47) | FLT3KITSRCNTRK1KDR | |
| SCHEMBL22917505 | 0.90 | FLT3 (0.47) | FLT3KITSRCNTRK1KDR | |
| SCHEMBL22917648 | 0.89 | CKS1B (0.47) | FLT3KITSRCNTRK1KDR | |
| SCHEMBL29911423 | 0.87 | FLT3 (0.46) | FLT3KITSRCNTRK1KDR | |
| SCHEMBL22917647 | 0.85 | KIT (0.55) | FLT3KITSRCNTRK1KDR | |
| SCHEMBL22917496 | 0.85 | FLT3 (0.43) | FLT3KITSRCNTRK1KDR | |
| SCHEMBL22917646 | 0.85 | FLT3 (0.43) | FLT3KITSRCNTRK1KDR | |
| SCHEMBL28912493 | 0.85 | FLT3 (0.43) | FLT3KITSRCNTRK1KDR | |
| SCHEMBL22917521 | 0.84 | FLT3 (0.42) | FLT3KITSRCNTRK1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3999064-A1 | INHIBITORS OF TYROSINE KINASE | Bridgene Biosciences, Inc. (US) | 2022-05-25 | — | — | EP | disclosed |