Rsm-932A Cation

Rsm-932A Cation

SCHEMBL29616554

CN(c1ccc(Cl)cc1)c1cc[n+](Cc2ccc(-c3ccc(C[n+]4ccc(N(C)c5ccc(Cl)cc5)c5ccccc54)cc3)cc2)c2ccccc12.[Br-].[Br-]

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

CHKA

The experimentally established mechanism targets of Rsm-932A Cation. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHKA known ✓ P35790 20/20 1.00
CHKB Q9Y259 2/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Rsm-932A Cation SCHEMBL16441051 0.99 CHKA (1.00) CHKACHKB
Rsm-932A Cation SCHEMBL29941165 0.99 CHKA (1.00) CHKACHKB
Bromide SCHEMBL2223547 0.93 CHKA (1.00) CHKACHKB
Bromide SCHEMBL2218483 0.81 CHKA (1.00) CHKACHKB
Bromide SCHEMBL612817 0.76 CHKA (0.61) CHKACHKB
SCHEMBL3164086 0.75 CHKA (0.61) CHKACHKB
SCHEMBL14182537 0.69 CHKA (0.54) CHKACHKB
Bromide SCHEMBL2223549 0.69 CHKA (0.53) CHKACHKB
Bromide SCHEMBL2220815 0.69 CHKA (0.61) CHKACHKB
Water SCHEMBL14740004 0.68 CHKA (0.97) CHKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4662319-A2 PERSONALIZED CRISPR PROFILING FOR CANCER Integrate Bioscience LLC (US) 2025-12-17 EP disclosed
US-12458659-B2 Methods for treating macrophage-mediated diseases, and methods of identifying agents useful therefore THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-11-04 US disclosed
CN-118671122-A Quick screening and identifying method for active ingredients of Chinese herbal medicines 中国科学院精密测量科学与技术创新研究院 2024-09-20 CN disclosed
WO-2024168301-A2 PERSONALIZED CRISPR PROFILING FOR CANCER FUNCTION ONCOLOGY, INC. (US) 2024-08-15 WO disclosed
CN-116178258-B N-methylaniline quinoline compound and synthetic method and application thereof 中国医学科学院北京协和医院 2023-11-21 CN disclosed
CN-116178258-A N-methylaniline quinoline compound and synthetic method and application thereof 中国医学科学院北京协和医院 2023-05-30 CN disclosed
US-20220133770-A1 METHODS FOR TREATING MACROPHAGE-MEDIATED DISEASES, AND METHODS OF IDENTIFYING AGENTS USEFUL THEREFORE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2022-05-05 US disclosed