SCHEMBL29617112

SCHEMBL29617112

CN(CCOCCOc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O)C(=O)OCc1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 13/20 0.62
DDB1 Q16531 12/20 0.62
MAP1LC3B Q9GZQ8 3/20 0.52
STAT3 P40763 1/20 0.50
AR P10275 1/20 0.49
IKZF3 Q9UKT9 3/20 0.49
GSK3B P49841 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23705631 1.00 CRBN (0.62) CRBNDDB1MAP1LC3BSTAT3AR
SCHEMBL22150447 0.86 CRBN (0.76) CRBNDDB1MAP1LC3BSTAT3AR
SCHEMBL23133984 0.86 CRBN (0.76) CRBNDDB1MAP1LC3BSTAT3AR
SCHEMBL23124803 0.86 CRBN (0.76) CRBNDDB1MAP1LC3BSTAT3AR
SCHEMBL22276487 0.85 CRBN (0.75) CRBNDDB1MAP1LC3BSTAT3AR
SCHEMBL20294800 0.85 CRBN (0.75) CRBNDDB1MAP1LC3BSTAT3IKZF3
SCHEMBL20294798 0.85 CRBN (0.75) CRBNDDB1MAP1LC3BSTAT3IKZF3
SCHEMBL30830842 0.84 CRBN (0.68) CRBNDDB1MAP1LC3BSTAT3AR
SCHEMBL27314606 0.82 CRBN (0.64) CRBNDDB1MAP1LC3BSTAT3AR
SCHEMBL22500886 0.82 CRBN (0.75) CRBNDDB1MAP1LC3BSTAT3AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115335373-B Compounds and uses thereof 福宏治疗公司 2025-05-20 CN disclosed
CN-116867785-A Compounds and uses thereof 福宏治疗公司 2023-10-10 CN disclosed
EP-4097096-A2 COMPOUNDS AND USES THEREOF Foghorn Therapeutics Inc. (US) 2022-12-07 EP disclosed
WO-2022109396-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. (US) 2022-05-27 WO disclosed