SCHEMBL29617347

SCHEMBL29617347

CCOC(=O)C(CC)C1c2ccccc2-c2ccccc21

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.51
TSHR P16473 3/20 0.51
CYP2C19 P33261 1/20 0.44
PIN1 Q13526 1/20 0.41
POLB P06746 2/20 0.41
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
NPC1 O15118 1/20 0.41
ALDH1A1 P00352 3/20 0.39
MAPT P10636 1/20 0.39
MMP8 P22894 1/20 0.39
KDM4E B2RXH2 1/20 0.39
HSD17B10 Q99714 1/20 0.39
IDO1 P14902 1/20 0.39
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29617349 1.00 CYP1A2 (0.51) CYP1A2TSHRCYP2C19PIN1POLB
SCHEMBL28637793 1.00 CYP1A2 (0.51) CYP1A2TSHRCYP2C19PIN1POLB
SCHEMBL27894880 0.86 TSHR (0.68) CYP1A2TSHRCYP2C19PIN1POLB
SCHEMBL2457716 0.86 TSHR (0.51) CYP1A2TSHRCYP2C19PIN1POLB
SCHEMBL19465642 0.83 CYP1A2 (0.46) CYP1A2TSHRCYP2C19PIN1POLB
SCHEMBL6974072 0.83 TSHR (0.46) CYP1A2TSHRCYP2C19PIN1POLB
SCHEMBL29617345 0.82 CYP1A2 (0.45) CYP1A2TSHRCYP2C19PIN1POLB
SCHEMBL28926885 0.82 CYP1A2 (0.45) CYP1A2TSHRCYP2C19PIN1POLB
SCHEMBL25301977 0.81 CYP1A2 (0.44) CYP1A2TSHRCYP2C19PIN1POLB
SCHEMBL30522607 0.81 CYP1A2 (0.44) CYP1A2TSHRCYP2C19PIN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3994144-A1 A NEW PROCESS FOR SYNTHESIZING C2 BRIDGED CYCLOPENTADIENYL LIGANDS AND CORRESPONDING ANSA-METALLOCENE CATALYSTS Haldia Petrochemicals Limited (IN) 2022-05-11 EP disclosed