Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 7/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 5/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5355395 | 1.00 | HTR2A (0.54) | HTR2ACA1CA2TDO2HRH1 | |
| SCHEMBL31026220 | 0.88 | HTR2A (0.52) | HTR2ACA1CA2TDO2HRH1 | |
| SCHEMBL14759063 | 0.88 | HTR2A (0.52) | HTR2ACA1CA2TDO2HRH1 | |
| SCHEMBL5820544 | 0.86 | HTR2A (0.50) | HTR2ACA1CA2TDO2HRH1 | |
| SCHEMBL28267036 | 0.85 | HTR2A (0.41) | HTR2ACA1CA2TDO2SLC6A2 | |
| SCHEMBL5353138 | 0.85 | HTR2A (0.64) | HTR2ACA1CA2TDO2HRH1 | |
| SCHEMBL2786275 | 0.85 | HTR2A (0.48) | HTR2ACA1CA2TDO2HRH1 | |
| SCHEMBL7574105 | 0.82 | HTR2A (0.61) | HTR2ACA1CA2TDO2HRH1 | |
| SCHEMBL17022715 | 0.82 | HTR2A (0.61) | HTR2ACA1CA2TDO2HRH1 | |
| SCHEMBL28270374 | 0.81 | HTR2A (0.41) | HTR2ACA1CA2TDO2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3994144-A1 | A NEW PROCESS FOR SYNTHESIZING C2 BRIDGED CYCLOPENTADIENYL LIGANDS AND CORRESPONDING ANSA-METALLOCENE CATALYSTS | Haldia Petrochemicals Limited (IN) | 2022-05-11 | — | — | EP | disclosed |