SCHEMBL29617488

SCHEMBL29617488

c1ccc2c(c#1)-c1ccccc1CCCC2

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.43
HPGD P15428 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MAOA P21397 2/20 0.41
MAOB P27338 2/20 0.41
CYP2A6 P11509 1/20 0.41
NOS3 P29474 2/20 0.37
DRD4 P21917 1/20 0.37
CES1 P23141 1/20 0.36
CYP19A1 P11511 3/20 0.33
CYP11B1 P15538 3/20 0.33
CYP11B2 P19099 3/20 0.33
MAPT P10636 1/20 0.33
MIF P14174 1/20 0.33
ALDH1A1 P00352 2/20 0.32
GAA P10253 1/20 0.32
ALOX12 P18054 1/20 0.32
NOS2 P35228 1/20 0.32
PDPK1 O15530 1/20 0.32
PARP1 P09874 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31679535 0.75 CYP2A6 (0.43) TSHRHPGDL3MBTL1MAOAMAOB
SCHEMBL31430380 0.72 TSHR (0.71) TSHRHPGDL3MBTL1MAOAMAOB
SCHEMBL568779 0.72 TSHR (0.71) TSHRHPGDL3MBTL1MAOAMAOB
SCHEMBL30731351 0.70 TSHR (0.67) TSHRHPGDL3MBTL1MAOAMAOB
SCHEMBL31621255 0.70 TSHR (0.67) TSHRHPGDL3MBTL1MAOAMAOB
SCHEMBL30436120 0.70 TSHR (0.67) TSHRHPGDL3MBTL1MAOAMAOB
SCHEMBL29593589 0.70 TSHR (0.67) TSHRHPGDL3MBTL1MAOAMAOB
SCHEMBL31135519 0.70 TSHR (0.67) TSHRHPGDL3MBTL1MAOAMAOB
SCHEMBL30668198 0.70 TSHR (0.67) TSHRHPGDL3MBTL1MAOAMAOB
SCHEMBL30505637 0.67 CYP2A6 (0.68) TSHRHPGDL3MBTL1MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110687178-B Mycobacterium tuberculosis CFP-10 antigen immunosensor and preparation method and application thereof 南京市第二医院 2022-06-07 CN claimed
CN-110687178-B Mycobacterium tuberculosis CFP-10 antigen immunosensor and preparation method and application thereof 南京市第二医院 2022-06-07 CN disclosed