Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL418143 | 1.00 | KDM4E (0.33) | KDM4EGPR3ALDH1A1TSHRHSD17B10 | |
| Water SCHEMBL28095816 | 0.98 | KDM4E (0.32) | KDM4EGPR3ALDH1A1TSHRHSD17B10 | |
| SCHEMBL976367 | 0.84 | KDM4E (0.40) | KDM4EGPR3ALDH1A1HSD17B10TDP1 | |
| SCHEMBL30343302 | 0.83 | KDM4E (0.39) | KDM4EGPR3TDP1 | |
| D-Glutamate SCHEMBL2036307 | 0.80 | MC4R (0.36) | KDM4EALDH1A1TSHRCYP1A2ACHE | |
| SCHEMBL28440790 | 0.77 | TDP1 (0.35) | KDM4EGPR3TDP1CYP2A6CYP1A2 | |
| SCHEMBL15994595 | 0.72 | TDP1 (0.39) | KDM4EGPR3ALDH1A1TSHRHSD17B10 | |
| SCHEMBL27575535 | 0.69 | HPRT1 (0.41) | KDM4EALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL1893653 | 0.68 | HSD17B10 (0.41) | KDM4EALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL23018970 | 0.68 | CYP2A6 (0.36) | ALDH1A1CYP2A6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4247937-A1 | METHODS OF IMPROVING PRODUCTION OF MORPHINAN ALKALOIDS AND DERIVATIVES | Antheia, Inc. (US) | 2023-09-27 | — | — | EP | disclosed |
| CN-115304611-A | Two pairs of dihydrobenzophenanthridine alkaloid compounds in radix zanthoxyli and extraction method and application thereof | 广西师范大学 | 2022-11-08 | — | — | CN | disclosed |
| CN-111171039-B | Oxidative dehydrogenation method of compound with cell nucleus targeting light activation imaging and cancer cell killing capacity and application | 华南理工大学 | 2022-10-25 | — | — | CN | disclosed |
| WO-2022109194-A1 | METHODS OF IMPROVING PRODUCTION OF MORPHINAN ALKALOIDS AND DERIVATIVES | ANTHEIA, INC. (US) | 2022-05-27 | — | — | WO | disclosed |