Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 1.00 |
| ▸ | BTK | Q06187 | 10/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18665600 | 1.00 | EGFR (1.00) | EGFRBTK | |
| SCHEMBL21316378 | 0.89 | EGFR (0.79) | EGFRBTK | |
| SCHEMBL18665709 | 0.88 | EGFR (1.00) | EGFRBTK | |
| SCHEMBL18665707 | 0.87 | EGFR (1.00) | EGFRBTK | |
| SCHEMBL18665651 | 0.86 | EGFR (1.00) | EGFRBTK | |
| SCHEMBL18665661 | 0.85 | BTK (1.00) | EGFRBTK | |
| SCHEMBL18665570 | 0.83 | EGFR (1.00) | EGFRBTK | |
| SCHEMBL18665605 | 0.83 | EGFR (1.00) | EGFRBTK | |
| SCHEMBL29817882 | 0.83 | EGFR (0.71) | EGFRBTK | |
| SCHEMBL29098961 | 0.83 | EGFR (0.71) | EGFRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114685516-A | Pyrazolopyrimidine derivatives as BTK inhibitors for the treatment of cancer | 洛克索肿瘤学股份有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-108431007-B | Pyrazolopyrimidine derivatives as BTK inhibitors for the treatment of cancer | 洛克索肿瘤学股份有限公司 | 2022-06-07 | — | — | CN | disclosed |