SCHEMBL29617993

SCHEMBL29617993

CC(C)c1ccc(N2c3ccccc3Sc3ccccc32)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 1/20 0.50
CYP1A2 P05177 3/20 0.47
KMT2A Q03164 2/20 0.47
HPGD P15428 2/20 0.47
MAOA P21397 2/20 0.47
MEN1 O00255 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
MGLL Q99685 1/20 0.46
PTGS1 P23219 3/20 0.45
PTGS2 P35354 2/20 0.45
BCHE P06276 7/20 0.44
HTR1A P08908 4/20 0.44
DRD3 P35462 4/20 0.44
HTR2A P28223 2/20 0.44
HTR2C P28335 2/20 0.44
HTR2B P41595 2/20 0.44
HTR6 P50406 2/20 0.44
ADRB3 P13945 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12536831 1.00 HDAC6 (0.50) HDAC6CYP1A2KMT2AHPGDMAOA
SCHEMBL18365077 0.90 KMT2A (0.51) HDAC6CYP1A2KMT2AHPGDMAOA
SCHEMBL17278625 0.89 HDAC6 (0.46) HDAC6CYP1A2KMT2AHPGDMAOA
SCHEMBL12536861 0.88 ITGB2 (0.47) CYP1A2KMT2AMEN1CYP2C19NPSR1
SCHEMBL1102436 0.85 BCHE (0.42) HDAC6CYP1A2KMT2AHPGDMAOA
SCHEMBL20152507 0.85 BCHE (0.42) HDAC6CYP1A2KMT2AHPGDMAOA
SCHEMBL12536842 0.85 CYP1A2 (0.50) HDAC6CYP1A2KMT2AHPGDMEN1
SCHEMBL12536839 0.85 BCHE (0.39) HDAC6CYP1A2KMT2AHPGDMAOA
SCHEMBL12190901 0.84 HDAC6 (0.62) HDAC6KMT2AMAOAMEN1PTGS1
SCHEMBL29851224 0.84 HDAC6 (0.62) HDAC6KMT2AMAOAMEN1PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113026036-B Method for synthesizing sulfur ylide compounds by using continuous flow electrochemical oxidation 南京工业大学 2022-06-07 CN disclosed