Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23366831 | 0.97 | EPHX1 (0.51) | BTKKMT2AALDH1A1MEN1TSHR | |
| SCHEMBL923552 | 0.95 | EPHX1 (0.54) | BTKKMT2AALDH1A1MEN1TSHR | |
| SCHEMBL9931314 | 0.93 | KMT2A (0.50) | BTKKMT2AALDH1A1MEN1TSHR | |
| SCHEMBL27799448 | 0.85 | KMT2A (0.45) | BTKKMT2AALDH1A1MEN1TSHR | |
| SCHEMBL23366889 | 0.85 | KMT2A (0.45) | BTKKMT2AALDH1A1MEN1TSHR | |
| SCHEMBL745045 | 0.85 | EPHX1 (0.54) | BTKKMT2AALDH1A1MEN1TSHR | |
| SCHEMBL29874054 | 0.84 | BTK (0.43) | BTKKMT2AALDH1A1MEN1TSHR | |
| SCHEMBL23367354 | 0.84 | BTK (0.43) | BTKKMT2AALDH1A1MEN1TSHR | |
| SCHEMBL3988278 | 0.81 | EPHX1 (0.57) | BTKKMT2AALDH1A1MEN1TSHR | |
| SCHEMBL3763770 | 0.80 | EPHX1 (0.60) | BTKKMT2AALDH1A1MEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022093820-A1 | SUBSTITUTED MORPHOLINE COMPOUNDS | GENENTECH, INC. (US) | 2022-05-05 | — | — | WO | disclosed |