Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 2/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | FPR3 | P25089 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31663771 | 1.00 | CHRNB4 (0.41) | CHRNB4CHRNA3ALOX5APFEN1ALDH1A1 | |
| SCHEMBL29619117 | 1.00 | CHRNB4 (0.41) | CHRNB4CHRNA3ALOX5APFEN1ALDH1A1 | |
| SCHEMBL13419614 | 0.86 | ALOX5AP (0.47) | CHRNB4CHRNA3ALOX5APFEN1ALDH1A1 | |
| SCHEMBL29619163 | 0.84 | ALOX5AP (0.45) | ALOX5APFEN1ALDH1A1UCHL1MEN1 | |
| SCHEMBL31663762 | 0.84 | ALOX5AP (0.45) | ALOX5APFEN1ALDH1A1UCHL1MEN1 | |
| SCHEMBL29619008 | 0.84 | ALOX5AP (0.45) | ALOX5APFEN1ALDH1A1UCHL1MEN1 | |
| SCHEMBL4371494 | 0.84 | ALOX5AP (0.45) | CHRNB4CHRNA3ALOX5APFEN1ALDH1A1 | |
| SCHEMBL4371497 | 0.84 | ALOX5AP (0.45) | CHRNB4CHRNA3ALOX5APFEN1ALDH1A1 | |
| SCHEMBL31663816 | 0.83 | ALOX5AP (0.41) | CHRNB4CHRNA3ALOX5APFEN1ALDH1A1 | |
| SCHEMBL4367102 | 0.83 | ALOX5AP (0.44) | CHRNB4CHRNA3ALOX5APFEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4236942-A1 | ISOXAZOLE DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | Arena Pharmaceuticals, Inc. (US) | 2023-09-06 | — | — | EP | disclosed |
| WO-2022093850-A1 | ISOXAZOLE DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2022-05-05 | — | — | WO | disclosed |