Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 7/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 4/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 3/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23212986 | 1.00 | CHRM4 (0.56) | CHRM4CHRM1CHRM2CHRM5DRD2 | |
| SCHEMBL23212991 | 1.00 | CHRM4 (0.56) | CHRM4CHRM1CHRM2CHRM5DRD2 | |
| SCHEMBL23213232 | 0.92 | CHRM4 (0.56) | CHRM4CHRM1CHRM2CHRM5DRD2 | |
| SCHEMBL23213231 | 0.92 | CHRM4 (0.56) | CHRM4CHRM1CHRM2CHRM5DRD2 | |
| SCHEMBL23213255 | 0.89 | CHRM4 (0.54) | CHRM4CHRM1CHRM2CHRM5DRD2 | |
| SCHEMBL23213257 | 0.89 | CHRM4 (0.54) | CHRM4CHRM1CHRM2CHRM5DRD2 | |
| SCHEMBL23212967 | 0.88 | CHRM4 (0.44) | CHRM4CHRM1CHRM2CHRM5DRD2 | |
| SCHEMBL23212964 | 0.88 | CHRM4 (0.44) | CHRM4CHRM1CHRM2CHRM5DRD2 | |
| SCHEMBL23213542 | 0.88 | CHRM4 (0.68) | CHRM4CHRM1CHRM2CHRM5DRD2 | |
| SCHEMBL29619693 | 0.88 | CHRM4 (0.44) | CHRM4CHRM1CHRM2CHRM5DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119390705-A | 5-Oxa-2-azaspiro [3.4] octane derivatives as M4 agonists | 诺华股份有限公司 | 2025-02-07 | — | — | CN | disclosed |
| CN-114555606-B | 5-Oxa-2-azaspiro [3.4] octane derivatives as M4 agonists | 诺华股份有限公司 | 2024-10-01 | — | — | CN | disclosed |
| CN-114555606-A | 5-oxa-2-azaspiro [3.4] octane derivatives as M4 agonists | 诺华股份有限公司 | 2022-05-27 | — | — | CN | disclosed |