Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 11/20 | 0.65 |
| ▸ | CHRM1 | P11229 | 9/20 | 0.65 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.54 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.54 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | RAF1 | P04049 | 2/20 | 0.32 |
| ▸ | BRAF | P15056 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29619721 | 0.93 | CHRM4 (0.68) | CHRM4CHRM1CHRM2CHRM5ATR | |
| SCHEMBL23213342 | 0.91 | CHRM4 (0.59) | CHRM4CHRM1CHRM2CHRM5ATR | |
| SCHEMBL23213347 | 0.91 | CHRM4 (0.59) | CHRM4CHRM1CHRM2CHRM5ATR | |
| SCHEMBL26781253 | 0.87 | CHRM4 (0.63) | CHRM4CHRM1CHRM2CHRM5CCNT1 | |
| SCHEMBL23213345 | 0.86 | CHRM4 (0.59) | CHRM4CHRM1CHRM2CHRM5DRD2 | |
| SCHEMBL23213429 | 0.84 | CHRM4 (0.55) | CHRM4CHRM1CHRM2CHRM5DRD2 | |
| SCHEMBL23213430 | 0.84 | CHRM4 (0.55) | CHRM4CHRM1CHRM2CHRM5DRD2 | |
| SCHEMBL23213199 | 0.83 | CHRM4 (0.68) | CHRM4CHRM1CHRM2CHRM5ATR | |
| SCHEMBL23213103 | 0.83 | CHRM4 (0.54) | CHRM4CHRM1CHRM2CHRM5DRD2 | |
| SCHEMBL23213201 | 0.83 | CHRM4 (0.68) | CHRM4CHRM1CHRM2CHRM5ATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119390705-A | 5-Oxa-2-azaspiro [3.4] octane derivatives as M4 agonists | 诺华股份有限公司 | 2025-02-07 | — | — | CN | disclosed |
| CN-114555606-B | 5-Oxa-2-azaspiro [3.4] octane derivatives as M4 agonists | 诺华股份有限公司 | 2024-10-01 | — | — | CN | disclosed |
| CN-114555606-A | 5-oxa-2-azaspiro [3.4] octane derivatives as M4 agonists | 诺华股份有限公司 | 2022-05-27 | — | — | CN | disclosed |