Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDE | P14735 | 5/20 | 0.54 |
| ▸ | TACR1 | P25103 | 1/20 | 0.53 |
| ▸ | MC4R | P32245 | 2/20 | 0.53 |
| ▸ | MC3R | P41968 | 2/20 | 0.53 |
| ▸ | MC1R | Q01726 | 2/20 | 0.53 |
| ▸ | MC5R | P33032 | 1/20 | 0.53 |
| ▸ | TERT | O14746 | 3/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
| ▸ | NPY1R | P25929 | 3/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
| ▸ | FURIN | P09958 | 1/20 | 0.47 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.47 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.47 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30177494 | 0.91 | FURIN (0.56) | IDETACR1MC4RMC3RMC1R | |
| Pabetan SCHEMBL29359620 | 0.91 | MC4R (0.56) | IDETACR1MC4RMC3RMC1R | |
| Pabetan SCHEMBL1738816 | 0.91 | MC4R (0.56) | IDETACR1MC4RMC3RMC1R | |
| Pabetan SCHEMBL23784701 | 0.91 | MC4R (0.56) | IDETACR1MC4RMC3RMC1R | |
| Pabetan SCHEMBL29646525 | 0.90 | MC4R (0.55) | IDETACR1MC4RMC3RMC1R | |
| SCHEMBL25455582 | 0.86 | MC4R (0.56) | IDEMC4RMC3RMC1RMC5R | |
| Hydrochloric Acid SCHEMBL29618972 | 0.85 | MCHR1 (0.58) | IDEMC4RMC3RMC1RMC5R | |
| SCHEMBL25453635 | 0.84 | MC4R (0.54) | IDETACR1MC4RMC3RMC1R | |
| SCHEMBL29749843 | 0.83 | PRMT1 (0.48) | TACR1MC4RMC3RMC1RMC5R | |
| SCHEMBL27352129 | 0.82 | NPY4R (0.47) | TACR1MC4RMC3RMC1RNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119604526-A | Anti-Adrenomedullin (ADM) antibodies or anti-ADM antibody fragments or anti-ADM non-Ig scaffolds for the treatment or prevention of shock | 艾德里诺医药公司 | 2025-03-11 | — | — | CN | disclosed |
| CN-119072492-A | Stable aqueous formulations of anti-Adrenomedullin (ADM) antibodies or anti-ADM antibody fragments | 艾德里诺医药公司 | 2024-12-03 | — | — | CN | disclosed |