⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31268347 | 1.00 | — | — | |
| SCHEMBL30497349 | 1.00 | — | — | |
| SCHEMBL30497369 | 1.00 | — | — | |
| SCHEMBL30497377 | 0.80 | — | — | |
| SCHEMBL30497379 | 0.80 | — | — | |
| SCHEMBL30497411 | 0.78 | — | — | |
| SCHEMBL10650241 | 0.78 | — | — | |
| SCHEMBL24553695 | 0.76 | — | — | |
| SCHEMBL30497378 | 0.76 | — | — | |
| SCHEMBL11168681 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12202836-B2 | Bicyclic-fused heteroaryl or aryl compounds | PFIZER INC. (US) | 2025-01-21 | — | — | US | disclosed |
| US-20230339960-A1 | Bicyclic-Fused Heteroaryl or Aryl Compounds | PFIZER (US) | 2023-10-26 | — | — | US | disclosed |
| US-11702424-B2 | Bicyclic-fused heteroaryl or aryl compounds | PFIZER INC. (US) | 2023-07-18 | — | — | US | disclosed |
| CN-110612298-B | Thienopyridines and benzothiophenes as IRAK4 inhibitors | 百时美施贵宝公司 | 2023-05-05 | — | — | CN | disclosed |
| US-20220213086-A1 | AZOLE COMPOUNDS AS IRAK INHIBITORS, PREPARATION METHODS AND MEDICINAL USES THEREOF | Eternity Bioscience Inc. | 2022-07-07 | — | — | US | disclosed |
| US-20220177446-A1 | ALKYNE COMPOUNDS AS IRAK INHIBITORS, PREPARATION METHODS AND MEDICINAL USES THEREOF | Eternity Bioscience Inc. | 2022-06-09 | — | — | US | disclosed |