SCHEMBL29620413

SCHEMBL29620413

Cc1cc(F)c(Br)cc1Br

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 6/20 0.45
KDM1B Q8NB78 4/20 0.45
KCNH2 Q12809 2/20 0.34
BCHE P06276 1/20 0.33
CES1 P23141 1/20 0.33
RAPGEF4 Q8WZA2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
ACHE P22303 1/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
MAPT P10636 1/20 0.32
NFKB1 P19838 1/20 0.32
RAB9A P51151 1/20 0.32
NFKB2 Q00653 1/20 0.32
KMT2A Q03164 1/20 0.32
RELA Q04206 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10456466 1.00 KDM1A (0.45) KDM1AKDM1BKCNH2BCHECES1
SCHEMBL850836 0.89 KDM1A (0.50) KDM1AKDM1BKCNH2BCHECES1
SCHEMBL30711810 0.86 KDM1A (0.52) KDM1AKDM1BKCNH2RAPGEF4ALDH1A1
SCHEMBL833057 0.86 KDM1A (0.52) KDM1AKDM1BKCNH2RAPGEF4ALDH1A1
SCHEMBL1224640 0.86 KDM1A (0.38) KDM1AKDM1BKCNH2BCHECES1
SCHEMBL29478809 0.86 KDM1A (0.38) KDM1AKDM1BKCNH2BCHECES1
SCHEMBL3565431 0.83 KDM1A (0.41) KDM1AKDM1BKCNH2BCHECES1
SCHEMBL1478306 0.83 KDM1A (0.45) KDM1AKDM1BKCNH2RAPGEF4ALDH1A1
SCHEMBL30578349 0.83 KDM1A (0.41) KDM1AKDM1BKCNH2BCHECES1
SCHEMBL30228644 0.83 KDM1A (0.45) KDM1AKDM1BKCNH2RAPGEF4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112573990-B Preparation method of 4-halogenated-3-fluorotoluene 沈阳中化农药化工研发有限公司 2022-05-06 CN disclosed