Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.31 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.31 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24345439 | 1.00 | POLB (0.34) | POLBMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL29620701 | 0.94 | POLB (0.36) | POLBMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL24345670 | 0.94 | POLB (0.36) | POLBMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL24345855 | 0.94 | POLB (0.36) | POLBMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL24345453 | 0.93 | POLB (0.35) | POLBMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL29620711 | 0.93 | POLB (0.35) | POLBMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL24345268 | 0.93 | POLB (0.35) | POLBMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL24345459 | 0.89 | POLB (0.39) | POLBMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL24345669 | 0.88 | POLB (0.38) | POLBMEN1HPGDKMT2ALMNA | |
| SCHEMBL24345270 | 0.88 | POLB (0.38) | POLBMEN1HPGDKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022086840-A1 | HETEROCYCLIC COMPOUNDS AS ANTI-VIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. (US) | 2022-04-28 | — | — | WO | disclosed |