Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 14/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.31 |
| ▸ | ULK1 | O75385 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24345472 | 1.00 | POLB (0.35) | POLBNAMPTDYRK1AMEN1HPGD | |
| SCHEMBL24346314 | 1.00 | POLB (0.35) | POLBNAMPTDYRK1AMEN1HPGD | |
| SCHEMBL24345858 | 0.91 | POLB (0.35) | POLBNAMPTDYRK1AMEN1HPGD | |
| SCHEMBL29620716 | 0.91 | POLB (0.35) | POLBNAMPTDYRK1AMEN1HPGD | |
| SCHEMBL24345316 | 0.91 | POLB (0.35) | POLBNAMPTDYRK1AMEN1HPGD | |
| SCHEMBL24345297 | 0.91 | POLB (0.34) | POLBNAMPT | |
| SCHEMBL24345459 | 0.91 | POLB (0.39) | POLBDYRK1AMEN1HPGDKMT2A | |
| SCHEMBL24345870 | 0.91 | POLB (0.36) | POLBNAMPTDYRK1AMEN1HPGD | |
| SCHEMBL24345300 | 0.90 | NAMPT (0.37) | POLBNAMPT | |
| SCHEMBL29620714 | 0.90 | NAMPT (0.37) | POLBNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022086840-A1 | HETEROCYCLIC COMPOUNDS AS ANTI-VIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. (US) | 2022-04-28 | — | — | WO | disclosed |