Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.31 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.31 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CFTR | P13569 | 2/20 | 0.31 |
| ▸ | NAMPT | P43490 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24345846 | 1.00 | POLB (0.37) | POLBMEN1KMT2AHPGDMAPK13 | |
| SCHEMBL29620711 | 0.93 | POLB (0.35) | POLBMEN1KMT2AHPGDMAPK13 | |
| SCHEMBL24345268 | 0.93 | POLB (0.35) | POLBMEN1KMT2AHPGDMAPK13 | |
| SCHEMBL24345453 | 0.93 | POLB (0.35) | POLBMEN1KMT2AHPGDMAPK13 | |
| SCHEMBL24346374 | 0.92 | POLB (0.35) | POLBMEN1KMT2AHPGDMAPK13 | |
| SCHEMBL29620704 | 0.92 | POLB (0.35) | POLBMEN1KMT2AHPGDMAPK13 | |
| SCHEMBL24346300 | 0.92 | POLB (0.35) | POLBMEN1KMT2AHPGDMAPK13 | |
| SCHEMBL24345845 | 0.89 | POLB (0.38) | POLBMEN1KMT2AHPGDADORA2A | |
| SCHEMBL24984688 | 0.88 | POLB (0.38) | POLBMEN1KMT2AHPGDLMNA | |
| SCHEMBL24986320 | 0.88 | POLB (0.38) | POLBMEN1KMT2AHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022086840-A1 | HETEROCYCLIC COMPOUNDS AS ANTI-VIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. (US) | 2022-04-28 | — | — | WO | disclosed |