Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MB | P02144 | 1/20 | 0.60 |
| ▸ | ABL1 | P00519 | 2/20 | 0.58 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.58 |
| ▸ | AURKA | O14965 | 1/20 | 0.58 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.58 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.58 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.58 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.58 |
| ▸ | CSF1R | P07333 | 1/20 | 0.58 |
| ▸ | RET | P07949 | 1/20 | 0.58 |
| ▸ | MET | P08581 | 1/20 | 0.58 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.58 |
| ▸ | PIM1 | P11309 | 1/20 | 0.58 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.58 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.58 |
| ▸ | FLT1 | P17948 | 1/20 | 0.58 |
| ▸ | LTK | P29376 | 1/20 | 0.58 |
| ▸ | GRK5 | P34947 | 1/20 | 0.58 |
| ▸ | KDR | P35968 | 1/20 | 0.58 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17081150 | 0.84 | MB (0.58) | MBABL1CHEK1AURKADAPK3 | |
| SCHEMBL20066164 | 0.81 | CDK5 (0.58) | MBABL1CHEK1AURKADAPK3 | |
| SCHEMBL152602 | 0.78 | GSK3B (0.58) | MBABL1CHEK1AURKADAPK3 | |
| SCHEMBL728499 | 0.78 | ABL1 (0.58) | MBABL1CHEK1AURKADAPK3 | |
| SCHEMBL5201194 | 0.78 | ABL1 (0.58) | MBABL1CHEK1AURKADAPK3 | |
| SCHEMBL23016925 | 0.78 | ABL1 (0.58) | MBABL1CHEK1AURKADAPK3 | |
| SCHEMBL13259405 | 0.78 | ABL1 (0.58) | MBABL1CHEK1AURKADAPK3 | |
| SCHEMBL2953884 | 0.77 | ABL1 (0.54) | MBABL1CHEK1AURKADAPK3 | |
| SCHEMBL13940835 | 0.77 | ABL1 (0.54) | MBABL1CHEK1AURKADAPK3 | |
| SCHEMBL5893559 | 0.77 | ABL1 (0.58) | ABL1CHEK1AURKADAPK3PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4240722-A1 | OXINDOLES AND METHODS OF USE THEREOF | Aligos Therapeutics, Inc. (US) | 2023-09-13 | — | — | EP | disclosed |
| WO-2022099066-A1 | OXINDOLES AND METHODS OF USE THEREOF | ALIGOS THERAPEUTICS, INC. (US) | 2022-05-12 | — | — | WO | disclosed |