Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GALR2 | O43603 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5786549 | 0.89 | MAPT (0.49) | MAPTALDH1A1KDM4ETDP1LMNA | |
| SCHEMBL5786539 | 0.89 | MAPT (0.49) | MAPTALDH1A1KDM4ETDP1LMNA | |
| SCHEMBL5786542 | 0.89 | MAPT (0.49) | MAPTALDH1A1KDM4ETDP1LMNA | |
| Potassium Ion SCHEMBL3930246 | 0.88 | MAPT (0.48) | MAPTALDH1A1KDM4ETDP1LMNA | |
| Potassium Ion SCHEMBL3930244 | 0.88 | MAPT (0.48) | MAPTALDH1A1KDM4ETDP1LMNA | |
| SCHEMBL18069254 | 0.84 | MAPT (0.58) | MAPTALDH1A1KDM4ETDP1LMNA | |
| SCHEMBL24358978 | 0.80 | STAT3 (0.52) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL4069118 | 0.79 | MAPT (0.44) | MAPTALDH1A1KDM4ETDP1LMNA | |
| SCHEMBL28979235 | 0.79 | MAPT (0.55) | MAPTALDH1A1KDM4ETDP1LMNA | |
| SCHEMBL5782741 | 0.76 | MAPT (0.51) | MAPTALDH1A1TDP1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022087624-A1 | COMPOUNDS AS RAS INHIBITORS AND USES THEREOF | BIOARDIS LLC (US) | 2022-04-28 | — | — | WO | disclosed |