Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 18/20 | 0.83 |
| ▸ | JAK1 | P23458 | 8/20 | 0.63 |
| ▸ | JAK2 | O60674 | 5/20 | 0.63 |
| ▸ | STAT6 | P42226 | 1/20 | 0.59 |
| ▸ | TYK2 | P29597 | 2/20 | 0.57 |
| ▸ | KDR | P35968 | 1/20 | 0.56 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22261166 | 1.00 | JAK3 (0.83) | JAK3JAK1JAK2STAT6TYK2 | |
| SCHEMBL22261158 | 0.91 | JAK3 (0.83) | JAK3JAK1JAK2STAT6TYK2 | |
| SCHEMBL30455447 | 0.91 | JAK3 (0.83) | JAK3JAK1JAK2STAT6TYK2 | |
| SCHEMBL22261266 | 0.90 | JAK3 (0.68) | JAK3JAK1JAK2STAT6TYK2 | |
| SCHEMBL29622941 | 0.90 | JAK3 (0.68) | JAK3JAK1JAK2STAT6TYK2 | |
| SCHEMBL22261190 | 0.89 | JAK3 (0.81) | JAK3JAK1JAK2STAT6TYK2 | |
| SCHEMBL29622875 | 0.89 | JAK3 (0.81) | JAK3JAK1JAK2STAT6TYK2 | |
| SCHEMBL23088804 | 0.88 | JAK3 (0.81) | JAK3JAK1JAK2STAT6TYK2 | |
| SCHEMBL29622776 | 0.88 | JAK3 (0.81) | JAK3JAK1JAK2STAT6TYK2 | |
| SCHEMBL22261225 | 0.88 | JAK3 (0.79) | JAK3JAK1JAK2TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3686197-B1 | 2-SUBSTITUTED PYRAZOLE AMINO-4-SUBSTITUTED AMINO-5-PYRIMIDINE FORMAMIDE COMPOUND, COMPOSITION, AND APPLICATION THEREOF | BEIJING SCITECH MQ PHARMACEUTICALS LTD (CN) | 2023-06-21 | — | — | EP | disclosed |
| US-11344549-B2 | 2-substituted pyrazole amino-4-substituted amino-5-pyrimidine formamide compound, composition, and application thereof | BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED (CN) | 2022-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11344549-B2 | 2-substituted pyrazole amino-4-substituted amino-5-pyrimidine formamide compound, composition, and application thereof | JAK1, JAK3, JAK2 | JAK3 2/4885JAK1 1/4885JAK2 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.