Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.54 |
| ▸ | AKT1 | P31749 | 1/20 | 0.54 |
| ▸ | STAT6 | P42226 | 7/20 | 0.52 |
| ▸ | JAK3 | P52333 | 6/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | JAK1 | P23458 | 1/20 | 0.48 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22261345 | 1.00 | RPS6KB1 (0.54) | RPS6KB1AKT1STAT6JAK3JAK2 | |
| SCHEMBL4188524 | 0.90 | CSNK2A2 (0.51) | RPS6KB1AKT1STAT6JAK3CSNK2A2 | |
| Hydrochloric Acid SCHEMBL4178767 | 0.89 | CSNK2A2 (0.50) | RPS6KB1AKT1STAT6JAK3CSNK2A2 | |
| SCHEMBL22261198 | 0.89 | JAK3 (0.62) | RPS6KB1AKT1STAT6JAK3JAK2 | |
| SCHEMBL22261068 | 0.89 | JAK2 (0.59) | RPS6KB1STAT6JAK3JAK2JAK1 | |
| SCHEMBL29622999 | 0.89 | JAK3 (0.62) | RPS6KB1AKT1STAT6JAK3JAK2 | |
| SCHEMBL23088806 | 0.87 | JAK3 (0.61) | RPS6KB1STAT6JAK3JAK2JAK1 | |
| SCHEMBL29622760 | 0.87 | JAK3 (0.61) | RPS6KB1STAT6JAK3JAK2JAK1 | |
| SCHEMBL22261134 | 0.86 | JAK3 (0.62) | RPS6KB1STAT6JAK3AURKAAURKB | |
| SCHEMBL29622769 | 0.86 | JAK3 (0.62) | RPS6KB1STAT6JAK3AURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3686197-B1 | 2-SUBSTITUTED PYRAZOLE AMINO-4-SUBSTITUTED AMINO-5-PYRIMIDINE FORMAMIDE COMPOUND, COMPOSITION, AND APPLICATION THEREOF | BEIJING SCITECH MQ PHARMACEUTICALS LTD (CN) | 2023-06-21 | — | — | EP | disclosed |
| US-11344549-B2 | 2-substituted pyrazole amino-4-substituted amino-5-pyrimidine formamide compound, composition, and application thereof | BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED (CN) | 2022-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11344549-B2 | 2-substituted pyrazole amino-4-substituted amino-5-pyrimidine formamide compound, composition, and application thereof | JAK1, JAK3, JAK2 | RPS6KB1 2079/4885AKT1 469/4885STAT6 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.