Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.44 |
| ▸ | PRCP | P42785 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2192515 | 1.00 | TSHR (0.48) | TSHRSLC18A3IDO1BLMEPHX1 | |
| SCHEMBL29182252 | 1.00 | TSHR (0.48) | TSHRSLC18A3IDO1BLMEPHX1 | |
| SCHEMBL2192471 | 0.98 | EPHX1 (0.46) | TSHRSLC18A3IDO1BLMEPHX1 | |
| SCHEMBL59026 | 0.94 | IDO1 (0.53) | TSHRSLC18A3IDO1BLMEPHX1 | |
| SCHEMBL29449692 | 0.94 | IDO1 (0.53) | TSHRSLC18A3IDO1BLMEPHX1 | |
| SCHEMBL3596545 | 0.94 | IDO1 (0.53) | TSHRSLC18A3IDO1BLMEPHX1 | |
| SCHEMBL3583014 | 0.94 | IDO1 (0.53) | TSHRSLC18A3IDO1BLMEPHX1 | |
| Bromide SCHEMBL9033434 | 0.92 | IDO1 (0.52) | TSHRSLC18A3IDO1BLMEPHX1 | |
| Hydrochloric Acid SCHEMBL22770167 | 0.92 | IDO1 (0.55) | TSHRSLC18A3IDO1BLMEPHX1 | |
| Benzene SCHEMBL28873131 | 0.92 | IDO1 (0.52) | TSHRIDO1BLMCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111265663-B | Application of orphanin enkephalin receptor specific antagonist in preparation of arrhythmia treatment drug | 郭政 | 2022-04-22 | — | — | CN | claimed |
| CN-111265663-B | Application of orphanin enkephalin receptor specific antagonist in preparation of arrhythmia treatment drug | 郭政 | 2022-04-22 | — | — | CN | disclosed |
| CN-111265663-B | Application of orphanin enkephalin receptor specific antagonist in preparation of arrhythmia treatment drug | 郭政 | 2022-04-22 | — | — | CN | disclosed |