Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 5/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.41 |
| ▸ | MAP3K7 | O43318 | 2/20 | 0.41 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23065072 | 1.00 | ACP1 (0.52) | ACP1ACHEMEN1ALDH1A1KMT2A | |
| SCHEMBL23065073 | 0.97 | ACP1 (0.48) | ACP1ACHEAVPR1B | |
| SCHEMBL29623222 | 0.90 | KMT2A (0.47) | ACP1MEN1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL24089977 | 0.90 | KMT2A (0.47) | ACP1MEN1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL23065098 | 0.89 | MEN1 (0.52) | ACP1ACHEMEN1ALDH1A1KMT2A | |
| SCHEMBL29623188 | 0.89 | MEN1 (0.52) | ACP1ACHEMEN1ALDH1A1KMT2A | |
| SCHEMBL24090101 | 0.89 | ACP1 (0.51) | ACP1ALDH1A1AVPR1B | |
| SCHEMBL24407885 | 0.88 | ACP1 (0.42) | ACP1MEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL23045336 | 0.87 | ACP1 (0.40) | ACP1 | |
| SCHEMBL23045335 | 0.87 | NPC1 (0.40) | ACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114650986-A | 2-aminoquinazolinone derivatives | 住友制药株式会社 | 2022-06-21 | — | — | CN | claimed |
| CN-114650986-A | 2-aminoquinazolinone derivatives | 住友制药株式会社 | 2022-06-21 | — | — | CN | disclosed |