Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 14/20 | 0.75 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | SRC | P12931 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19350790 | 1.00 | FGFR1 (0.75) | FGFR1MAPTALDH1A1SMN1; SMN2SRC | |
| Morpholine SCHEMBL20604013 | 0.88 | FGFR1 (0.59) | FGFR1MAPTALDH1A1SMN1; SMN2SRC | |
| SCHEMBL29623676 | 0.86 | FGFR1 (0.71) | FGFR1MAPTALDH1A1SMN1; SMN2SRC | |
| SCHEMBL19350718 | 0.86 | FGFR1 (0.71) | FGFR1MAPTALDH1A1SMN1; SMN2SRC | |
| SCHEMBL7986395 | 0.86 | FGFR1 (0.80) | FGFR1SRC | |
| SCHEMBL29357610 | 0.86 | FGFR1 (1.00) | FGFR1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7989819 | 0.86 | FGFR1 (1.00) | FGFR1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL19350704 | 0.85 | FGFR1 (0.74) | FGFR1MAPTALDH1A1SMN1; SMN2SRC | |
| SCHEMBL19350907 | 0.85 | FGFR1 (0.70) | FGFR1MAPTALDH1A1SMN1; SMN2SRC | |
| SCHEMBL29623665 | 0.85 | FGFR1 (0.74) | FGFR1MAPTALDH1A1SMN1; SMN2SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071523-B | Urea compound, preparation method and medical application thereof | 恩瑞生物医药科技（上海）有限公司 | 2022-05-31 | — | — | CN | disclosed |