Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.92 |
| ▸ | ERBB2 | P04626 | 9/20 | 0.81 |
| ▸ | ERBB4 | Q15303 | 3/20 | 0.75 |
| ▸ | GAK | O14976 | 2/20 | 0.75 |
| ▸ | ABL1 | P00519 | 2/20 | 0.75 |
| ▸ | LCK | P06239 | 2/20 | 0.75 |
| ▸ | MET | P08581 | 2/20 | 0.75 |
| ▸ | PHKG2 | P15735 | 2/20 | 0.75 |
| ▸ | BLK | P51451 | 2/20 | 0.75 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.75 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.75 |
| ▸ | HIPK4 | Q8NE63 | 2/20 | 0.75 |
| ▸ | EPHA6 | Q9UF33 | 2/20 | 0.75 |
| ▸ | CIT | O14578 | 1/20 | 0.75 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.75 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.75 |
| ▸ | STK10 | O94804 | 1/20 | 0.75 |
| ▸ | LYN | P07948 | 1/20 | 0.75 |
| ▸ | RET | P07949 | 1/20 | 0.75 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10128118 | 1.00 | EGFR (0.92) | EGFRERBB2ERBB4GAKABL1 | |
| SCHEMBL14427867 | 1.00 | EGFR (0.92) | EGFRERBB2ERBB4GAKABL1 | |
| SCHEMBL14066601 | 0.97 | EGFR (0.87) | EGFRERBB2ERBB4GAKABL1 | |
| SCHEMBL1191715 | 0.97 | EGFR (0.91) | EGFRERBB2ERBB4GAKABL1 | |
| SCHEMBL1191713 | 0.97 | EGFR (0.91) | EGFRERBB2ERBB4GAKABL1 | |
| SCHEMBL1191712 | 0.97 | EGFR (0.91) | EGFRERBB2ERBB4GAKABL1 | |
| SCHEMBL14066620 | 0.97 | EGFR (0.85) | EGFRERBB2ERBB4GAKABL1 | |
| SCHEMBL14149370 | 0.96 | EGFR (0.96) | EGFRERBB2ERBB4GAKABL1 | |
| SCHEMBL15772053 | 0.96 | EGFR (0.96) | EGFRERBB2ERBB4GAKABL1 | |
| SCHEMBL18595838 | 0.96 | EGFR (1.00) | EGFRERBB2ERBB4GAKABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119403567-A | AMHR2-ED cancer vaccine formulation | 克利夫兰诊所基金会 | 2025-02-07 | — | — | CN | disclosed |
| US-20230312658-A1 | EPITOPE FOCUSING BY VARIABLE EFFECTIVE ANTIGEN SURFACE CONCENTRATION | CENTIVAX, INC. | 2023-10-05 | — | — | US | disclosed |
| EP-4218806-A1 | COMPOSITIONS AND KITS FOR ELICITING AN IMMUNE RESPONSE | Duke University (US) | 2023-08-02 | — | — | EP | disclosed |
| US-20220387582-A1 | Compositions, Methods and Kits for Eliciting an Immune Response | DUKE UNIVERSITY (US) | 2022-12-08 | — | — | US | disclosed |
| EP-3766517-B1 | COMPOSITIONS, METHODS, AND KITS FOR ELICITING AN IMMUNE RESPONSE | UNIV DUKE (US) | 2022-11-02 | — | — | EP | disclosed |
| CN-110713489-B | Heteroaryl SYK inhibitors | 勃林格殷格翰国际有限公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-110183440-B | Heteroaryl SYK inhibitors | 勃林格殷格翰国际有限公司 | 2022-04-22 | — | — | CN | disclosed |