Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21253025 | 0.79 | DAO (0.46) | DAOSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL18551846 | 0.78 | DAO (0.59) | DAOSLC6A4SLC6A2SLC6A3SKP2 | |
| SCHEMBL22129795 | 0.77 | TAAR1 (0.48) | S1PR1S1PR2S1PR3S1PR4 | |
| SCHEMBL22814961 | 0.77 | DAO (0.36) | DAOSLC6A4SKP2S1PR1S1PR2 | |
| SCHEMBL14157243 | 0.76 | TAAR1 (0.52) | DAOSLC6A4SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL9921243 | 0.76 | DAO (0.50) | DAOSLC6A4SLC6A2SLC6A3SKP2 | |
| Hydrochloric Acid SCHEMBL29507330 | 0.74 | TAAR1 (0.50) | DAOSLC6A4SLC6A2SLC6A3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28720337 | 0.74 | TAAR1 (0.50) | DAOSLC6A4SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL20382591 | 0.73 | SKP2 (0.56) | DAOSKP2ALDH1A1HTT | |
| SCHEMBL24288749 | 0.72 | TAAR1 (0.56) | DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003996-A1 | ESTROGEN RECEPTOR-MODULATING COMPOUNDS | Radius Pharmaceuticals, Inc. (US) | 2022-06-01 | — | — | EP | disclosed |